miRNA description for miR-21
miRNA accession miR-21
Species Mus musculus
 miR-21 identified in exosomes derived from the following tissue/cell type
Embryonic kidney cells [Extracellular vesicles] 34315885   
Embryonic kidney cells [Extracellular vesicles] 34315885   
Kidney epithelial cells [Extracellular vesicles] 34315885   
Kidney epithelial cells [Extracellular vesicles] 34315885   
Mast cells [Exosomes] 17486113   
Neuronal cells [Exosomes] 22965126   
Neuronal cells [Exosomes] 22965126   
Neuronal cells [Exosomes] 22965126   
Neuronal cells [Exosomes] 22965126   
Neuronal cells [Exosomes] 22965126   
 Experiment description of studies that identified miR-21 in exosomes
1
Experiment ID2525
Identified moleculemiRNA
Identification method qRT-PCR
PubMed ID 34315885   
OrganismMus musculus
Experiment descriptionExtracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease
AuthorsDing H, Li LX, Harris PC, Yang J, Li X.
Journal name Nat Commun
Publication year2021
SampleEmbryonic kidney cells
Sample nameMEK - Pkd1 WT
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qRT-PCR
EV-TRACK -
2
Experiment ID2526
Identified moleculemiRNA
Identification method qRT-PCR
PubMed ID 34315885   
OrganismMus musculus
Experiment descriptionExtracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease
AuthorsDing H, Li LX, Harris PC, Yang J, Li X.
Journal name Nat Commun
Publication year2021
SampleEmbryonic kidney cells
Sample nameMEK - Pkd1-null
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qRT-PCR
EV-TRACK -
3
Experiment ID2521
Identified moleculemiRNA
Identification method qRT-PCR
PubMed ID 34315885   
OrganismMus musculus
Experiment descriptionExtracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease
AuthorsDing H, Li LX, Harris PC, Yang J, Li X.
Journal name Nat Commun
Publication year2021
SampleKidney epithelial cells
Sample namePN24 - postnatal homozygous Pkd1-null
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Immuno-EM
qRT-PCR
EV-TRACK -
4
Experiment ID2522
Identified moleculemiRNA
Identification method qRT-PCR
PubMed ID 34315885   
OrganismMus musculus
Experiment descriptionExtracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease
AuthorsDing H, Li LX, Harris PC, Yang J, Li X.
Journal name Nat Commun
Publication year2021
SampleKidney epithelial cells
Sample namePH2 - postnatal heterozygous Pkd1
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qRT-PCR
EV-TRACK -
5
Experiment ID15
Identified moleculemiRNA
Identification method miRCURY LNA Array
PubMed ID 17486113   
OrganismMus musculus
Homo sapiens
Experiment descriptionExosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
AuthorsValadi H, Ekströ, Bossios A, Sjöand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year2007
SampleMast cells
Sample nameMC9
Bone marrow-derived mast cells
HMC-1
Molecules identified in the studyProtein
mRNA
miRNA
Methods used in the studyMass spectrometry [MALDI TOF]
Western blotting
Microarray
MicroRNA array [miRCURY LNA Array]
EV-TRACK -
6
Experiment ID342
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 22965126   
OrganismMus musculus
Experiment descriptionSmall RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells.
AuthorsBellingham SA, Coleman BM, Hill AF
Journal name Nucleic Acids Res
Publication year2012
SampleNeuronal cells
Sample nameGT1-7 - Unifected Rep 1
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
Western blotting
EV-TRACK EV120028: EV-METRIC:22%
7
Experiment ID343
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 22965126   
OrganismMus musculus
Experiment descriptionSmall RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells.
AuthorsBellingham SA, Coleman BM, Hill AF
Journal name Nucleic Acids Res
Publication year2012
SampleNeuronal cells
Sample nameGT1-7 - Unifected Rep 2
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK EV120028: EV-METRIC:22%
8
Experiment ID344
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 22965126   
OrganismMus musculus
Experiment descriptionSmall RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells.
AuthorsBellingham SA, Coleman BM, Hill AF
Journal name Nucleic Acids Res
Publication year2012
SampleNeuronal cells
Sample nameGT1-7 - Prion infected Rep 1
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
Western blotting
EV-TRACK EV120028: EV-METRIC:22%
9
Experiment ID345
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 22965126   
OrganismMus musculus
Experiment descriptionSmall RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells.
AuthorsBellingham SA, Coleman BM, Hill AF
Journal name Nucleic Acids Res
Publication year2012
SampleNeuronal cells
Sample nameGT1-7 - Prion infected Rep 2
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK EV120028: EV-METRIC:22%
10
Experiment ID346
Identified moleculemiRNA
Identification method RNA deep sequencing
PubMed ID 22965126   
OrganismMus musculus
Experiment descriptionSmall RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells.
AuthorsBellingham SA, Coleman BM, Hill AF
Journal name Nucleic Acids Res
Publication year2012
SampleNeuronal cells
Sample nameGT1-7 - Prion infected and uninfected
Molecules identified in the studyProtein
miRNA
Methods used in the studyRNA deep sequencing
EV-TRACK EV120028: EV-METRIC:22%