miRNA description for miR-21 |
miRNA accession |
miR-21 |
Species |
Mus musculus |
miR-21 identified in exosomes derived from the following tissue/cell type |
Embryonic kidney cells [Extracellular vesicles]
|
34315885
|
Embryonic kidney cells [Extracellular vesicles]
|
34315885
|
Kidney epithelial cells [Extracellular vesicles]
|
34315885
|
Kidney epithelial cells [Extracellular vesicles]
|
34315885
|
Mast cells [Exosomes]
|
17486113
|
Neuronal cells [Exosomes]
|
22965126
|
Neuronal cells [Exosomes]
|
22965126
|
Neuronal cells [Exosomes]
|
22965126
|
Neuronal cells [Exosomes]
|
22965126
|
Neuronal cells [Exosomes]
|
22965126
|
Experiment description of studies that identified miR-21 in exosomes |
1
|
Experiment ID | 2525 |
Identified molecule | miRNA
|
Identification method | qRT-PCR
|
PubMed ID |
34315885
|
Organism | Mus musculus |
Experiment description | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease |
Authors | Ding H, Li LX, Harris PC, Yang J, Li X. |
Journal name |
Nat Commun
|
Publication year | 2021 |
Sample | Embryonic kidney cells |
Sample name | MEK - Pkd1 WT |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting qRT-PCR |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 2526 |
Identified molecule | miRNA
|
Identification method | qRT-PCR
|
PubMed ID |
34315885
|
Organism | Mus musculus |
Experiment description | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease |
Authors | Ding H, Li LX, Harris PC, Yang J, Li X. |
Journal name |
Nat Commun
|
Publication year | 2021 |
Sample | Embryonic kidney cells |
Sample name | MEK - Pkd1-null |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting qRT-PCR |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 2521 |
Identified molecule | miRNA
|
Identification method | qRT-PCR
|
PubMed ID |
34315885
|
Organism | Mus musculus |
Experiment description | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease |
Authors | Ding H, Li LX, Harris PC, Yang J, Li X. |
Journal name |
Nat Commun
|
Publication year | 2021 |
Sample | Kidney epithelial cells |
Sample name | PN24 - postnatal homozygous Pkd1-null |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting Immuno-EM qRT-PCR |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 2522 |
Identified molecule | miRNA
|
Identification method | qRT-PCR
|
PubMed ID |
34315885
|
Organism | Mus musculus |
Experiment description | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease |
Authors | Ding H, Li LX, Harris PC, Yang J, Li X. |
Journal name |
Nat Commun
|
Publication year | 2021 |
Sample | Kidney epithelial cells |
Sample name | PH2 - postnatal heterozygous Pkd1 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting qRT-PCR |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 15 |
Identified molecule | miRNA
|
Identification method | miRCURY LNA Array
|
PubMed ID |
17486113
|
Organism | Mus musculus Homo sapiens |
Experiment description | Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. |
Authors | Valadi H, Ekströ, Bossios A, Sjöand M, Lee JJ, Lotvall JO |
Journal name |
NCB
|
Publication year | 2007 |
Sample | Mast cells |
Sample name | MC9 Bone marrow-derived mast cells HMC-1 |
Molecules identified in the study | Protein mRNA miRNA |
Methods used in the study | Mass spectrometry [MALDI TOF] Western blotting Microarray MicroRNA array [miRCURY LNA Array] |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 342 |
Identified molecule | miRNA
|
Identification method | RT-PCR
|
PubMed ID |
22965126
|
Organism | Mus musculus |
Experiment description | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. |
Authors | Bellingham SA, Coleman BM, Hill AF |
Journal name |
Nucleic Acids Res
|
Publication year | 2012 |
Sample | Neuronal cells |
Sample name | GT1-7 - Unifected Rep 1 |
Molecules identified in the study | miRNA |
Methods used in the study | RT-PCR Western blotting |
EV-TRACK |
EV120028: EV-METRIC:22%
|
|
|
7
|
Experiment ID | 343 |
Identified molecule | miRNA
|
Identification method | RT-PCR
|
PubMed ID |
22965126
|
Organism | Mus musculus |
Experiment description | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. |
Authors | Bellingham SA, Coleman BM, Hill AF |
Journal name |
Nucleic Acids Res
|
Publication year | 2012 |
Sample | Neuronal cells |
Sample name | GT1-7 - Unifected Rep 2 |
Molecules identified in the study | miRNA |
Methods used in the study | RT-PCR |
EV-TRACK |
EV120028: EV-METRIC:22%
|
|
|
8
|
Experiment ID | 344 |
Identified molecule | miRNA
|
Identification method | RT-PCR
|
PubMed ID |
22965126
|
Organism | Mus musculus |
Experiment description | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. |
Authors | Bellingham SA, Coleman BM, Hill AF |
Journal name |
Nucleic Acids Res
|
Publication year | 2012 |
Sample | Neuronal cells |
Sample name | GT1-7 - Prion infected Rep 1 |
Molecules identified in the study | miRNA |
Methods used in the study | RT-PCR Western blotting |
EV-TRACK |
EV120028: EV-METRIC:22%
|
|
|
9
|
Experiment ID | 345 |
Identified molecule | miRNA
|
Identification method | RT-PCR
|
PubMed ID |
22965126
|
Organism | Mus musculus |
Experiment description | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. |
Authors | Bellingham SA, Coleman BM, Hill AF |
Journal name |
Nucleic Acids Res
|
Publication year | 2012 |
Sample | Neuronal cells |
Sample name | GT1-7 - Prion infected Rep 2 |
Molecules identified in the study | miRNA |
Methods used in the study | RT-PCR |
EV-TRACK |
EV120028: EV-METRIC:22%
|
|
|
10
|
Experiment ID | 346 |
Identified molecule | miRNA
|
Identification method | RNA deep sequencing
|
PubMed ID |
22965126
|
Organism | Mus musculus |
Experiment description | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. |
Authors | Bellingham SA, Coleman BM, Hill AF |
Journal name |
Nucleic Acids Res
|
Publication year | 2012 |
Sample | Neuronal cells |
Sample name | GT1-7 - Prion infected and uninfected |
Molecules identified in the study | Protein miRNA |
Methods used in the study | RNA deep sequencing |
EV-TRACK |
EV120028: EV-METRIC:22%
|
|
|